Studies on Immunity to Pneumococcus Mucosus (type Iii)

نویسنده

  • William S. Tillett
چکیده

1. Immunization of rabbits with Type III pneumococci is effective in producing active immunity against infection with a virulent strain of the homologous organism. 2. Immunization of rabbits with Type I or II pneumococci, and with R forms derived from any of the fixed types, is equally effective in producing active immunity against Type III infection. 3. Immunization of rabbits with nucleoprotein or with desoxycholate solutions of heterologous pneumococci, under the experimental conditions described, appears to be ineffective in producing active immunity against Type III infection.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

An Immunological Study of Pneumococcus Mucosus

1. The organisms described by Schottmüller under the name Streptococcus mucosus represent a well defined group with characteristics which indicate a closer relationship to the pneumococci than to the streptococci. 2. The members of this group are specifically agglutinable when treated according to the method of Porges. They do not agglutinate when subjected to the usual agglutination methods. 3...

متن کامل

Studies on Natural Immunity to Pneumococcus Type Iii Iv. Observations on a Non-type Specific Humoral Factor Involved in Resistance to Pneumococcus Type Iii By

Experimental evidence presented in Paper III* indicates that removal and destruction of both rabbit virulent and avirulent strains of Pneumococcus Type III in the normal animal are brought about by the same means, namely, the phagocytic cells of the body, provided the integrity of the capsule becomes impaired. It leaves unanswered, however, the interesting q~aestion as to whether this phagocyto...

متن کامل

Chemo-immunological Studies on Conjugated Carbohydrate-proteins

1. Type-specific antipneumococcus immunity has been induced in rabbits by immunization with antigen prepared by combining a specific derivative of the capsular polysaccharide of Type III Pneumococcus with globulin from horse serum. 2. Rabbits immunized with this antigen acquire active immunity against infection with virulent Type III pneumococci. 3. The sera of the immune rabbits contain type-s...

متن کامل

The Application of the Reaction of Agglutination to the Pneumococcus

Owing to unavoidable circumstances only a limited amount of time was available for the work on agglutination. The foregoing report is therefore preliminary only and the following conclusions are provisionally offered: I. Pneumococci by reason of their agglutinating properties exhibit a tendency to separate into numerous groups similar to streptococci. II. Pneumococcus mucosus forms a distinct a...

متن کامل

STUDIES ON PNEUMOCOCCUS IMMUNITY. II. ACTIVE IMMUNIZATION 01~ MONKEYS AGAINST PNEIIMOCOCCUS TYPES II, III, AND IV PNEtr~ONIA W~T~ ~_E HOMOLOOOVS

In a previous communication (1) i t has been shown tha t the subcutaneous or in t ravenous injection of monkeys with Pneumococcus Type I vaccine confers on them a complete immuni ty against experimenta l Pneumococcus Type I pneumonia. In this article the results of similar experiments with Pnettmococcus Types II , I I I , and IV will be reported. Two species of monkeys have been employed in the...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • The Journal of Experimental Medicine

دوره 45  شماره 

صفحات  -

تاریخ انتشار 2003